Hyperelastic Nanocellulose-Reinforced Hydrogel of High Water Content for Ophthalmic Applications
2016 (English)In: ACS Biomaterials Science and Engineering, ISSN 2373-9878, Vol. 2, no 11, 2072-2079 p.Article in journal (Refereed) Published
A nanocellulose-reinforced poly(vinyl alcohol) hydrogel material of exceptionally high water content for ophthalmic applications is presented (>90 wt %), which also features a hitherto unprecedented combination of optical, mechanical, viscoelastic, oxygen permeability, and biocompatibility properties. The hydrogel combines the desired softness with remarkable strain-dependent mechanical strength and thereby demonstrates hyperelastic, rubber-like mechanical properties. The observed unusual mechanical behavior is due to both high water content and the combination of relatively stiff cellulose nanowhiskers entangled in a soft polymer matrix of poly(vinyl alcohol) (PVA), thus mimicking the structural characteristics of the cornea's main constituents, i.e., water and collagen.
Place, publisher, year, edition, pages
2016. Vol. 2, no 11, 2072-2079 p.
biocompatibility, cellulose nanocrystals, contact lens, ophthalmic prosthesis, poly(vinyl alcohol)
Research subject Engineering Science with specialization in Nanotechnology and Functional Materials
IdentifiersURN: urn:nbn:se:uu:diva-310474DOI: 10.1021/acsbiomaterials.6b00484ISI: 000388161200027ScopusID: 2-s2.0-84995379882OAI: oai:DiVA.org:uu-310474DiVA: diva2:1057044
FunderKnut and Alice Wallenberg FoundationVINNOVA, 2013-04645