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Synthesis of some C-11-labelled MAO-A inhibitors and their in vivo uptake kinetics in rhesus monkey brain
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
1997 (English)In: NUCLEAR MEDICINE AND BIOLOGY, Vol. 24, no 5, 381-388 p.Other (Other scientific)
Abstract [en]

Five potential MAO-A inhibitors-harmine, N-methyl-harmine, harmaline, brofaromine, and clorgyline-were labelled with C-11 and their brain kinetics evaluated in vivo in rhesus monkey using PET. The compounds were synthesized by alkylation with C-11 methyl

Place, publisher, year, pages
PERGAMON-ELSEVIER SCIENCE LTD , 1997. Vol. 24, no 5, 381-388 p.
Keyword [en]
positron emission tomography; MAO-A; clorgyline; harmine; brofaromine; POSITRON EMISSION TOMOGRAPHY; HARMAN BINDING EXPERIMENTS; OXIDASE SUBTYPE-A; MONOAMINE-OXIDASE; B ACTIVITY; RAT; BROFAROMINE; CNS; PET
Identifiers
URN: urn:nbn:se:uu:diva-77861OAI: oai:DiVA.org:uu-77861DiVA: diva2:105774
Note
Addresses: UPPSALA UNIV, SUBFEMTOMOLE BIORECOGNIT PROJECT, UPPSALA, SWEDEN. RES DEV CORP JAPAN, UPPSALA, SWEDEN. UPPSALA UNIV, DEPT CHEM, INST CHEM, UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17

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