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Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues
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1999 (English)In: JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, Vol. 42, no 20, 4150-4160 p.Article in journal (Other scientific) Published
Abstract [en]

The further development-of allosteric HIV-1 RT inhibitors in the urea analogue series of PETT (phenylethylthiazolylthiourea) derivatives is described here. The series includes derivatives with an ethyl linker (1-5) and racemic (6-16) and enantiomeric (17-

Place, publisher, year, edition, pages
1999. Vol. 42, no 20, 4150-4160 p.
Keyword [en]
IMMUNODEFICIENCY-VIRUS TYPE-1; NONNUCLEOSIDE INHIBITORS; WILD-TYPE; POTENT; DERIVATIVES; REPLICATION; COMBINATION; NEVIRAPINE; DRUG; ZIDOVUDINE
Identifiers
URN: urn:nbn:se:uu:diva-78134OAI: oai:DiVA.org:uu-78134DiVA: diva2:106047
Note
Addresses: Hogberg M, Medivir AB, Lunastigen 7, S-14144 Huddinge, Sweden. Medivir AB, S-14144 Huddinge, Sweden. Karolinska Inst, Ctr Microbiol & Tumor Biol, MTC, Stockholm, Sweden. Uppsala Univ, Dept Mol Biol, S-75124 Uppsala, Sweden.Available from: 2008-01-29 Created: 2008-01-29 Last updated: 2011-01-14

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Unge, TBackbro, K

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