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Shutdown in protein synthesis due to the expression of mini-genes in bacteria
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology.
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1999 (English)In: JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, Vol. 291, no 4, 745-759 p.Article in journal (Other scientific) Published
Abstract [en]

Mutants of Escherichia coli partially deficient in peptidyl-tRNA hydrolase are killed by the expression of certain very short open reading frames (mini-genes), encoded by the wild-type bar regions of phage lambda. According to the current hypothesis, prot

Place, publisher, year, edition, pages
ACADEMIC PRESS LTD , 1999. Vol. 291, no 4, 745-759 p.
Keyword [en]
peptidyl-tRNA hydrolase; mini-gene; translation termination; ribosome recycling; Shine-Dalgarno interaction; PEPTIDYL-TRANSFER-RNA; ESCHERICHIA-COLI RIBOSOMES; RELEASE FACTOR RF3; LACZ MESSENGER-RNA; GROWTH-INHIBITION; AMINO-ACID; TRANSLATION; EFFICIENCY;
URN: urn:nbn:se:uu:diva-78334OAI: oai:DiVA.org:uu-78334DiVA: diva2:106247
Addresses: Ehrenberg M, BMC, Dept Cell & Mol Biol, Box 596, S-75124 Uppsala, Sweden. BMC, Dept Cell & Mol Biol, S-75124 Uppsala, Sweden. Inst Biol Physicochim, UPR9073, CNRS, F-75005 Paris, France.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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