Purification of substance P endopeptidase (SPE) activity in human spinal cord and subsequent comparative studies with SPE in cerebrospinal fluid and with chymotrypsin
1998 (English)In: JOURNAL OF MOLECULAR RECOGNITION, ISSN 0952-3499, Vol. 11, no 1-6, 266-269 p.Article in journal (Other scientific) Published
An enzyme activity capable of hydrolysing the neuroactive undecapeptide substance P (SP) between its Phe(7)-Phe(8) residues was purified from the membrane-bound fraction of human spinal cords. The enzyme preparation yielded was compared with a previously
Place, publisher, year, edition, pages
1998. Vol. 11, no 1-6, 266-269 p.
substance P; endopeptidase; spinal cord; cerebrospinal fluid; human; purification; characterization; AKTA (TM); CONVERTING ENZYME; NEUTRAL ENDOPEPTIDASE; DEGRADING ENZYME
IdentifiersURN: urn:nbn:se:uu:diva-78745OAI: oai:DiVA.org:uu-78745DiVA: diva2:106658
Addresses: Uppsala Univ, Ctr Biomed, Dept Pharmaceut Biosci, Div Biol Res Drug Dependence, S-75124 Uppsala, Sweden.2005-06-012005-06-012011-01-14