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Retinoic acid receptor retinoid X receptor heterodimers can be activated through both subunits providing a basis for synergistic transactivation and cellular differentiation
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1997 (English)In: JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, Vol. 272, no 14, 9443-9449 p.Article in journal (Other scientific) Published
Abstract [en]

The receptor for 9-cis-retinoic acid, retinoid X receptor (RXR), forms heterodimers with several nuclear receptors, including the receptor for all-trans-retinoic acid, RAR. Previous studies have shown that retinoic acid receptor can be activated in RAR/RX

Place, publisher, year, edition, pages
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC , 1997. Vol. 272, no 14, 9443-9449 p.
Keyword [en]
THYROID-HORMONE RECEPTOR; LIGAND-BINDING DOMAIN; NUCLEAR RECEPTOR; CO-REPRESSOR; TRANSCRIPTIONAL ACTIVATION; RESPONSE PATHWAYS; CRYSTAL-STRUCTURE; LINE U-937; BETA-GENE; PROLIFERATION
Identifiers
URN: urn:nbn:se:uu:diva-79698OAI: oai:DiVA.org:uu-79698DiVA: diva2:107611
Note
Addresses: LUDWIG INST CANC RES, S-17177 STOCKHOLM, SWEDEN. UNIV UPPSALA, DEPT PATHOL, LAB TUMOR BIOL, S-75185 UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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