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Total synthesis of balanol .2. Completion of the synthesis and investigation of the structure and reactivity of two key heterocyclic intermediates.
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1997 (English)In: TETRAHEDRON, Vol. 53, no 13, 4857-4868 p.Other (Other scientific)
Abstract [en]

A convergent enantioselective total synthesis of the natural product (-)-balanol (1) is described. In addition to benzophenone fragment 8, key intermediates are chiral bicyclic aziridine 3 and the corresponding epoxide 4, both of which undergo highly reg

Place, publisher, year, pages
PERGAMON-ELSEVIER SCIENCE LTD , 1997. Vol. 53, no 13, 4857-4868 p.
Keyword [en]
PROTEIN-KINASE-C; SEMIEMPIRICAL METHODS; CHIRAL AZIRIDINES; PARAMETERS; EPOXIDES; OPTIMIZATION; OXAZOLINES; INHIBITOR; ANALOGS; RING
Identifiers
URN: urn:nbn:se:uu:diva-80012OAI: oai:DiVA.org:uu-80012DiVA: diva2:107926
Note
Addresses: Tanner D, TECH UNIV DENMARK, DEPT ORGAN CHEM, BLDG 201, DK-2800 LYNGBY, DENMARK. UNIV UPPSALA, DEPT ORGAN CHEM, S-75121 UPPSALA, SWEDEN. ASTRO DRACO AB, S-22100 LUND, SWEDEN. UNIV STOCKHOLM, ARRHENIUS LAB, S-10691 STOCKHOLM, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17

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