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VEGF receptor signalling: in control of vascular function
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
2006 (English)In: Nature reviews. Molecular cell biology, ISSN 1471-0072, Vol. 7, no 5, 359-371 p.Article in journal (Refereed) Published
Abstract [en]

Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system. VEGFR1 is required for the recruitment of haematopoietic precursors and migration of monocytes and macrophages, whereas VEGFR2 and VEGFR3 are essential for the functions of vascular endothelial and lymphendothelial cells, respectively. Recent insights have shed light onto VEGFR signal transduction and the interplay between different VEGFRs and VEGF co-receptors in development, adult physiology and disease.

Place, publisher, year, edition, pages
2006. Vol. 7, no 5, 359-371 p.
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Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-80191DOI: 10.1038/nrm1911PubMedID: 16633338OAI: oai:DiVA.org:uu-80191DiVA: diva2:108105
Available from: 2006-05-03 Created: 2006-05-03 Last updated: 2011-10-26Bibliographically approved

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Publisher's full textPubMedhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=16633338&dopt=Citation

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Olsson, Anna-KarinDimberg, AnnaKreuger, JohanClaesson-Welsh, Lena

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