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The dynamic structure of EF-G studied by fusidic acid resistance and internal revertants
Uppsala University. Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Molecular Biology.
Uppsala University. Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Molecular Biology.
1996 (English)In: JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, Vol. 258, no 3, 420-432 p.Article in journal (Other academic) Published
Abstract [en]

We have previously identified 20 different fusidic acid-resistant alleles of fusA, encoding mutant forms of the ribosomal translocase EF-G. One of these, P413L, is used here as the starting point in selections for internal revertants, identifying 20 diffe

Place, publisher, year, edition, pages
ACADEMIC PRESS LTD , 1996. Vol. 258, no 3, 420-432 p.
Keyword [en]
directed evolution; fusA; growth rate selection; protein dynamics; spectinomycin; SIGNAL RECOGNITION PARTICLE; ESCHERICHIA-COLI; 4.5S RNA; SALMONELLA-TYPHIMURIUM; ELONGATION; RIBONUCLEOPROTEIN; RIBOSOME; MUTANTS
Identifiers
URN: urn:nbn:se:uu:diva-80215OAI: oai:DiVA.org:uu-80215DiVA: diva2:108129
Note
Addresses: UPPSALA UNIV, DEPT MOLEC BIOL, CTR BIOMED, S-75124 UPPSALA, SWEDEN. LUND UNIV, DEPT MOLEC BIOPHYS, S-22100 LUND, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-07-08

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