The hTERT and hTERC telomerase gene promoters are activated by the second exon of the adenoviral protein, E1A, identifying the transcriptional corepressor CtBP as a potential repressor of both genes.
2005 (English)In: Neoplasia, ISSN 1522-8002, Vol. 7, no 6, 614-22 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2005. Vol. 7, no 6, 614-22 p.
Adenovirus E1A Proteins/*genetics, Blotting; Western, Cell Line, Chromatin/chemistry, DNA-Binding Proteins/*genetics, Exons, Gene Expression Regulation, Humans, Immunoprecipitation, Luciferases/metabolism, Macromolecular Substances, Models; Genetic, Mutagenesis; Site-Directed, Mutation, Phosphoproteins/*genetics, Plasmids/metabolism, Promoter Regions (Genetics), RNA/*genetics, Research Support; Non-U.S. Gov't, Sp1 Transcription Factor/metabolism, Telomerase/*genetics, Transcription; Genetic, Transfection
IdentifiersURN: urn:nbn:se:uu:diva-80323PubMedID: 16036112OAI: oai:DiVA.org:uu-80323DiVA: diva2:108237