Persistence of resistant Staphylococcus epidermidis after single course of clarithromycin
2005 (English)In: Emerging Infectious Diseases, ISSN 1080-6040, E-ISSN 1080-6059, Vol. 11, no 9, 1389-1393 p.Article in journal (Refereed) Published
We examined how a common therapy that includes clarithromycin affects normally colonizing Staphylococcus epidermidis. Samples from the nostrils of 5 patients receiving therapy were collected before, immediately after, 1 year after, and 4 years after treatment. From each patient and sample, S. epidermidis strains were isolated and analyzed for clarithromycin susceptibility and presence of the erm(C) gene. We show that macrolide-resistant strains of S. epidermidis were selected during therapy and that the same resistant strain may persist for 4 years, in the absence of further antimicrobial treatment.
Place, publisher, year, edition, pages
2005. Vol. 11, no 9, 1389-1393 p.
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-80368PubMedID: 16229767OAI: oai:DiVA.org:uu-80368DiVA: diva2:108282