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DISSOCIATION RATE OF COGNATE PEPTIDYL-TRANSFER-RNA FROM THE A-SITE OF HYPER-ACCURATE AND ERROR-PRONE RIBOSOMES
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Cell and Molecular Biology.
1994 (English)In: EUROPEAN JOURNAL OF BIOCHEMISTRY, ISSN 0014-2956, Vol. 226, no 2, 355-360 p.Article in journal (Other scientific) Published
Abstract [en]

The binding stability of the aminoacyl-tRNA site (A-site), estimated from the dissociation rate constant k(d), of AcPhe-Phe-tRNA(Phe) has been studied for wild-type (wt), for hyperaccurate ribosomes altered in S12 [streptomycin-dependent (SmD) and strepto

Place, publisher, year, edition, pages
SPRINGER VERLAG , 1994. Vol. 226, no 2, 355-360 p.
Keyword [en]
ALLOSTERIC 3-SITE MODEL; ESCHERICHIA-COLI; TRANSFER-RNA; ELONGATION CYCLE; GENE-EXPRESSION; MUTANTS; RESISTANT; DISCRIMINATION; GROWTH
Identifiers
URN: urn:nbn:se:uu:diva-80581OAI: oai:DiVA.org:uu-80581DiVA: diva2:108495
Note
Addresses: BIOMED CTR, DEPT MOLEC BIOL, S-75124 UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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