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ENHANCEMENT OF HIV-1 PROTEINASE ACTIVITY BY HIV-1 REVERSE-TRANSCRIPTASE
Uppsala University.
Uppsala University.
Uppsala University.
Uppsala University.
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1995 (English)In: VIROLOGY, ISSN 0042-6822, Vol. 206, no 1, 387-394 p.Article in journal (Other scientific) Published
Abstract [en]

HIV-1 reverse transcriptase (RT) was found to increase the activity of HIV-I proteinase in vitro and in eukaryotic cells. The effect of RT on proteinase activity was dose-dependent and independent of pH or salt concentration. The cleavage of sequences cor

Place, publisher, year, edition, pages
ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS , 1995. Vol. 206, no 1, 387-394 p.
Keyword [en]
IMMUNODEFICIENCY-VIRUS PROTEASE; RECOMBINANT VACCINIA VIRUS; ESCHERICHIA-COLI; GAG PRECURSOR; ASPARTIC PROTEASE; VIRAL INFECTIVITY; POL POLYPROTEINS; TYPE-1 PROTEASE; CLEAVAGE SITES; MATURATION
Identifiers
URN: urn:nbn:se:uu:diva-80614OAI: oai:DiVA.org:uu-80614DiVA: diva2:108528
Note
Addresses: GOOBARLARSSON L, KAROLINSKA INST, CTR MICROBIOL & TUMORBIOL, BOX 280, S-17177 STOCKHOLM, SWEDEN. UPPSALA UNIV, BMC, DEPT MOLEC BIOL, S-11111 UPPSALA, SWEDEN. MEDIVIR AB, S-14144 HUDDINGE, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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