HIV-infection and psychiatric illnesses: A double edged sword that threatens the vision of a contained epidemic The Greater Stockholm HIV Cohort Study
2017 (English)In: Journal of Infection, ISSN 0163-4453, E-ISSN 1532-2742, Vol. 74, no 1, 22-28 p.Article in journal (Refereed) Published
Context: The Greater Stockholm HIV Cohort Study is an initiative to provide longitudinal information regarding the health of people living with HIV. Objective: Our aim was to explore the prevalence of HIV and its association with psychiatric co-morbidities. Design, setting and participants: All patients with a recorded diagnosis of HIV ( any position of the ICD-10 codes B20-B24) were identified during the period 2007-2014 and related to the total population in Stockholm by January 1, 2015, N = 2.21 million. The age at diagnosis, gender, and first occurrence of an HIV diagnosis was recorded. Analyses were done by age and gender. Prevalence of psychiatric co-morbidities amongst HIV patients were recorded. Main outcome measures: Age-adjusted odds ratios with 95% confidence intervals were calculated with logistic regression for prevalent psychiatric co-morbidities in HIV infected individuals compared to the prevalence in the general population. Results: The total prevalence of HIV was 0.16%; females 0.10% (n Z 1134) and males 0.21% (n Z 2448). HIV-infected people were more frequently diagnosed with psychiatric illnesses and drug abuse. In females and males with HIV-diagnosis respectively, drug dependence disorder was 7.5 (7.76% vs 1.04%) and 5.1 (10.17% vs 1.98%) times higher, psychotic disorders were 6.3 (2.65% vs 0.42%) and 2.9 (1.43% vs 0.49%) times higher, bipolar disorder was 2.5 (1.41% vs 0.57%) and 3 (1.02% vs 0.34%) times higher, depression diagnosis was 1.5 (8.47% vs 5.82%) and 3.4 (10.17% vs 2.97%) higher, trauma-related disorder was 1.5 (6.00% vs 4.10%) respectively 2.9 (4.45% vs 1.56%) times higher, anxiety disorder was 1.2 (6.88% vs 5.72%) and 2.2 (6.54% vs 2.93%) times higher than in their non-infected peers. Conclusion: Despite effective ART, many individuals with HIV have an impaired mental health and a history of drug abuse that may threaten the vision of a contained epidemic. (C) 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
Place, publisher, year, edition, pages
W B SAUNDERS CO LTD , 2017. Vol. 74, no 1, 22-28 p.
Administrative databases, General population, Psychotic disorders, Bipolar disorders, Depression, Anxiety disorders, Trauma-related disorders, Drug dependence disorders, Gender, Epidemiology
IdentifiersURN: urn:nbn:se:uu:diva-319295DOI: 10.1016/j.jinf.2016.09.009ISI: 000396367000003PubMedID: 27717780OAI: oai:DiVA.org:uu-319295DiVA: diva2:1088169