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A new twist in Smad signaling
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Ludwig Institute for Cancer Research.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm , Ludwig Institute for Cancer Research.
2006 (English)In: Developmental Cell, ISSN 1534-5807, E-ISSN 1878-1551, Vol. 10, no 6, 685-686 p.Article in journal (Other academic) Published
Abstract [en]

Signaling by members of the TGFbeta family is much dependent on the common-mediator Smad4, which forms transcriptionally active complexes with all receptor-activated Smads (R-Smads). New findings demonstrate that transcriptional intermediary factor 1gamma (TIF1gamma) also can bind to R-Smads, as an alternative to Smad4, and mediate different transcriptional effects.

Place, publisher, year, edition, pages
2006. Vol. 10, no 6, 685-686 p.
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Medical and Health Sciences
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URN: urn:nbn:se:uu:diva-80916DOI: 10.1016/j.devcel.2006.05.006PubMedID: 16740469OAI: oai:DiVA.org:uu-80916DiVA: diva2:108830
Available from: 2006-06-20 Created: 2006-06-20 Last updated: 2017-12-14Bibliographically approved

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Heldin, Carl-HenrikMoustakas, Aristidis

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