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Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations.
Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Chemistry, Department of Physical and Analytical Chemistry, Physical Chemistry. Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Chemistry, Department of Physical and Analytical Chemistry. Avdelningen för fysikalisk kemi.
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2006 (English)In: Biochim Biophys Acta, ISSN 0006-3002, Vol. 1758, no 1, 55-64 p.Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 1758, no 1, 55-64 p.
Keyword [en]
Adenocarcinoma/drug therapy/metabolism, Animals, Chemistry; Pharmaceutical, Cryoelectron Microscopy, Female, Half-Life, Humans, Ionophores/chemistry, Kinetics, Lipids/*chemistry/pharmacokinetics, Liposomes/*chemistry/metabolism, Mice, Mice; Inbred ICR, Research Support; Non-U.S. Gov't, Time Factors, Vincristine/*chemistry/pharmacokinetics/pharmacology
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URN: urn:nbn:se:uu:diva-81681PubMedID: 16487476OAI: oai:DiVA.org:uu-81681DiVA: diva2:109596
Available from: 2006-08-30 Created: 2006-08-30 Last updated: 2011-01-11

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Edwards, KatarinaKarlsson, Göran

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