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First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmacy.
Uppsala University, Medicinska vetenskapsområdet, Faculty of Pharmacy, Department of Pharmacy.
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2006 (English)In: Drug Metab Dispos, ISSN 0090-9556, Vol. 34, no 7, p. 1182-9Article in journal (Refereed) Published
Place, publisher, year, edition, pages
2006. Vol. 34, no 7, p. 1182-9
Keywords [en]
Animals, Antipyrine/pharmacokinetics, Bile/metabolism, Calcium Channel Blockers/*pharmacology, Comparative Study, Dose-Response Relationship; Drug, Histamine H1 Antagonists/blood/*pharmacokinetics, Intestinal Absorption/*drug effects, Liver/*drug effects/metabolism, Models; Animal, Perfusion, Research Support; Non-U.S. Gov't, Swine, Terfenadine/*analogs & derivatives/blood/pharmacokinetics, Verapamil/*pharmacology
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URN: urn:nbn:se:uu:diva-81952PubMedID: 16621934OAI: oai:DiVA.org:uu-81952DiVA, id: diva2:109867
Available from: 2007-11-08 Created: 2007-11-08 Last updated: 2011-01-11

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Bergman, EbbaHedeland, MikaelBondesson, UlfLennernäs, Hans

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Department of PharmacyDepartment of Medicinal Chemistry

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