Insight in frontotemporal dementia: Conceptual analysis and empirical evaluation of the consensus criterion “loss of insight” in frontotemporal dementia
2007 (English)In: Brain and Cognition, ISSN 0278-2626, E-ISSN 1090-2147, Vol. 63, no 1, 13-23 p.Article in journal (Refereed) Published
The objective of this study was to suggest a new formulation of the core research diagnostic consensus criterion “loss of insight” in frontotemporal dementia (FTD). Eight patients with FTD (diagnoses made by interviews, medical and neuropsychological examination, CT scan, and regional cerebral glucose metabolism measured by positron emission tomography (PET) participated in the study). The results indicated that insight was present in three out of eight patients, and that insight appears to be a heterogeneous concept. Two types of insight emerged: Emotional insight associated with frontotemporal functions, and cognitive insight, related to posterior cognitive functions. These results suggest that loss of insight should not serve as a core criterion on FTD, but serves well as a supportive criterion of the disease.
Place, publisher, year, edition, pages
2007. Vol. 63, no 1, 13-23 p.
Frontotemporal dementia, Consensus criterion “loss of insight”, Conceptual analysis, PET, Interview, Neuropsychology, Emotional and cognitive insight
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:uu:diva-83112DOI: 10.1016/j.bandc.2006.07.001ISI: 000244340400002PubMedID: 16914245OAI: oai:DiVA.org:uu-83112DiVA: diva2:111019