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Infektioner och behandling vid kroniska bensår: Antibiotikaförbrukningen alltför hög, restriktivitet förordas
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences.
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1999 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 96, no 1-2, 42-46 p.Article in journal (Refereed) Published
Abstract [en]

Chronic venous leg ulcers are contaminated or colonised with bacteria that seldom affects ulcer healing. Signs of clinical infection appear in only a minority of chronic ulcers. In spite of this, data show a high consumption of antibiotics in this group of patients. Treatment with antibiotics is indicated only when clinical signs of infection or obvious risk factors are present or when Streptococcus pyogenes is isolated from the ulcer. In these cases an oral antistaphylococcal agent (semisynthetic penicillinase-resistant penicillin or first generation oral cephalosporin) is recommended as the first choice. Enterococci, anaerobic bacteria and gram-negative bacteria including pseudomonas spp. often colonise chronic ulcers, but do not usually cause antibiotic requiring infection.

Place, publisher, year, edition, pages
1999. Vol. 96, no 1-2, 42-46 p.
Keyword [en]
Anti-Bacterial Agents/*administration & dosage, Chronic Disease, Drug Utilization, English Abstract, Guidelines, Humans, Prescriptions; Drug, Varicose Ulcer/*drug therapy/microbiology/pathology, Wound Healing, Wound Infection/*drug therapy/microbiology/pathology
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-83418PubMedID: 9951248OAI: oai:DiVA.org:uu-83418DiVA: diva2:111326
Available from: 2006-11-02 Created: 2006-11-02Bibliographically approved

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