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Mechanical characteristics of nanocellulose-PEG bionanocomposite wound dressings in wet conditions
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Mechanics.
Norwegian Univ Sci & Technol NTNU, Dept Canc Res & Mol Med, Trondheim, Norway..
Norwegian Univ Sci & Technol NTNU, Dept Canc Res & Mol Med, Trondheim, Norway.;Trondheim Reg & Univ Hosp, St Olavs Hosp HF, Dept Dermatol, Trondheim, Norway..
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences, Applied Mechanics.
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2017 (English)In: Journal of The Mechanical Behavior of Biomedical Materials, ISSN 1751-6161, E-ISSN 1878-0180, Vol. 69, 377-384 p.Article in journal (Refereed) Published
Abstract [en]

Wood nanocellulose has been proposed for wound dressing applications partly based on its capability to form translucent films with good liquid absorption capabilities. Such properties are adequate for non-healing and chronic wounds where adequate management of exudates is a requirement. In addition, the translucency will allow to follow the wound development without the necessity to remove the dressing from the wound. Understanding the mechanical properties of nanocellulose films and dressings are also most important for tailoring optimizing wound dressing structures with adequate strength, conformability, porosity and exudate management. Mechanical properties are usually assessed in standard conditions (50% relative humidity, RH), which is not relevant in a wound management situation. In this study we have assessed the mechanical properties of three nanocellulose grades varying in the degree of nanofibrillation. The effect of nanofibrillation and of polyethylene glycol (PEG) addition, on the tensile strength, elongation and elastic modulus were assessed after 24 h in water and in phosphate-buffered saline (PBS). The results reveal the behavior of the nanocellulose dressings after wetting and shed light into the development of mechanical properties in environments, which are relevant from a wound management point of view.

Place, publisher, year, edition, pages
2017. Vol. 69, 377-384 p.
Keyword [en]
CNF, Nanocellulose, Bionanocomposites, Plasticizer, Mechanical properties
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:uu:diva-323443DOI: 10.1016/j.jmbbm.2017.01.049ISI: 000400199600041PubMedID: 28171794OAI: oai:DiVA.org:uu-323443DiVA: diva2:1120478
Available from: 2017-07-06 Created: 2017-07-06 Last updated: 2017-09-04Bibliographically approved
In thesis
1. Mechanical Properties and Deformation Behaviour of Polymer Materials during Nanosectioning: Characterisation and Modelling
Open this publication in new window or tab >>Mechanical Properties and Deformation Behaviour of Polymer Materials during Nanosectioning: Characterisation and Modelling
2017 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Research in local fracture processes and micro-machining of polymers and polymer-based composites has attracted increasing attention, in development of composite materials and miniaturisation of polymer components. In this thesis, sectioning (machining) of a glassy polymer and a carbon nanotube based composite at the nanoscale was performed by an instrumented ultramicrotome. The yield stresses and fracture toughness of these materials were determined by analysing the sectioning forces. Fractographic analysis by atomic force microscopy was conducted to characterise the topographies and elastic properties of the sectioned surfaces to explore the deformation and fracture behaviour of the polymer during nanosectioning. The study reveals that a transition from homogenous to shear localised deformation occurred as the uncut chip thickness (depth of cut) or sectioning speed increased to a critical value. Analytical and finite element methods were used to model the nanosectioning process. The shear localised deformation was caused by thermal softening due to plastic dissipation. Although not considering sectioning, the tensile properties of a polymer nanocomposite were additionally investigated, where the degree of nanofibrillation and polyethylene glycol (PEG) content had significant effects.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2017. 49 p.
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, ISSN 1651-6214 ; 1553
Keyword
Nanosectioning; Fracture toughness; Adiabatic shearing; Shear band; Nanosectioning; Glassy polymer; Nanocomposite
National Category
Applied Mechanics
Identifiers
urn:nbn:se:uu:diva-328906 (URN)978-91-513-0062-7 (ISBN)
Public defence
2017-10-20, Häggsalen Ångströmlaboratoriet, Lägerhyddsvägen 1, 752 37, Uppsala, 13:00 (English)
Opponent
Supervisors
Available from: 2017-09-21 Created: 2017-09-04 Last updated: 2017-10-18

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Sun, FengzhenGamstedt, Erik Kristofer

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