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Biochemical characterization of the 7 alpha-hydroxylase activities towards 27-hydroxycholesterol and dehydroepiandrosterone in pig liver microsomes
Uppsala University.
Uppsala University.
1998 (English)In: BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, Vol. 1390, no 3, 269-281 p.Other (Other scientific)
Abstract [en]

Microsomal cytochrome P450 catalyzing the 7 alpha-hydroxylation of 27-hydroxycholesterol and dehydroepiandrosterone was partially purified from pig liver. This enzyme fraction also catalyzed 7 alpha-hydroxylation of 25-hydroxycholesterol and pregnenolone

Place, publisher, year, pages
ELSEVIER SCIENCE BV , 1998. Vol. 1390, no 3, 269-281 p.
Keyword [en]
27-hydroxycholesterol; dehydroepiandrosterone; 7 alpha-hydroxylation; cytochrome P-450; liver microsome; steroid metabolism; BILE-ACID BIOSYNTHESIS; RAT-BRAIN MICROSOMES; CHOLESTEROL 7-ALPHA-HYDROXYLASE; TESTOSTERONE 7-ALPHA-HYDROXYLASE; 3-BETA-HYDROXY-
Identifiers
URN: urn:nbn:se:uu:diva-84795OAI: oai:DiVA.org:uu-84795DiVA: diva2:112703
Note
Addresses: Norlin M, Univ Uppsala, Dept Pharmaceut Biosci, Div Biochem, Box 578, S-75123 Uppsala, Sweden. Univ Uppsala, Dept Pharmaceut Biosci, Div Biochem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17

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