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6 alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes
Uppsala University.
Uppsala University.
1999 (English)In: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, Vol. 1438, no 1, 47-54 p.Other (Other scientific)
Abstract [en]

The aim of the present study was to identify the enzymes in human liver catalyzing hydroxylations of bile acids. Fourteen recombinant expressed cytochrome P450 (CYP) enzymes, human liver microsomes from different donors, and selective cytochrome P450 inh

Place, publisher, year, pages
ELSEVIER SCIENCE BV , 1999. Vol. 1438, no 1, 47-54 p.
Keyword [en]
bile acid; 6 alpha-hydroxylation; CYP3A4; human liver; BILE-ACIDS; PIG-LIVER; METABOLISM; URINE; CYTOCHROME-P-450; IDENTIFICATION; CHOLESTASIS; 6-BETA-HYDROXYLASE; HYDROXYLATIONS; CIRRHOSIS
Identifiers
URN: urn:nbn:se:uu:diva-84879OAI: oai:DiVA.org:uu-84879DiVA: diva2:112787
Note
Addresses: Araya Z, Univ Uppsala, Dept Pharmaceut Sci, Div Biochem, Box 578, S-75123 Uppsala, Sweden. Univ Uppsala, Dept Pharmaceut Sci, Div Biochem, S-75123 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17

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