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Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P
Uppsala University.
Uppsala University.
1996 (English)In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, Vol. 93, no 12, 6085-6090 p.Article in journal (Other scientific) Published
Abstract [en]

We have studied RNase P RNA (M1 RNA) cleavage of model tRNA precursors that are cleaved at two independent positions. Here we present data demonstrating that cleavage at both sites depends on the 2'-OH immediately 5' of the respective cleavage site. Howev

Place, publisher, year, edition, pages
NATL ACAD SCIENCES , 1996. Vol. 93, no 12, 6085-6090 p.
Keyword [en]
ribozyme; tRNA precursors; tRNA processing; RIBONUCLEASE-P; 2'-HYDROXYL GROUPS; PRECURSOR; INHIBITORS; SEQUENCES; SUBSTRATE; INVITRO; ENZYME; RIBOSE; GENES
Identifiers
URN: urn:nbn:se:uu:diva-84965OAI: oai:DiVA.org:uu-84965DiVA: diva2:112873
Note
Addresses: CTR BIOMED, DEPT MICROBIOL, S-75123 UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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