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Neonatal iron exposure induces neurobehavioural dysfunctions in adult mice
Uppsala University.
Uppsala University.
Uppsala University.
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1999 (English)In: TOXICOLOGY AND APPLIED PHARMACOLOGY, ISSN 0041-008X, Vol. 159, no 1, 25-30 p.Article in journal (Other scientific) Published
Abstract [en]

Excess iron in the brain has been implicated in the pathogenesis of several human neurodegenerative disorders, i.e., Parkinson's and Alzheimer's disease. The neonatal period is critical for the establishment of normal iron content in the adult brain. In t

Place, publisher, year, edition, pages
ACADEMIC PRESS INC , 1999. Vol. 159, no 1, 25-30 p.
Keyword [en]
iron supplementation; neonatal; Days 10-12; NMRI mice; Fe+2; high/low doses; locomotion; rearing; habituation; radial maze; errors; latency; deficits; total iron content; basal ganglia; parkinsonism; STRIATAL DOPAMINERGIC MARKERS; RAT SUBSTANTIA-NIGRA; PA
Identifiers
URN: urn:nbn:se:uu:diva-84983OAI: oai:DiVA.org:uu-84983DiVA: diva2:112891
Note
Addresses: Fredriksson A, Uppsala Univ, Dept Neurosci, S-75017 Uppsala, Sweden. Uppsala Univ, Dept Neurosci, S-75017 Uppsala, Sweden. UFRGS, Dept Bioquim, Porto Alegre, RS, Brazil. Uppsala Univ, Dept Environm Toxicol, S-75017 Uppsala, Sweden. Gothenburg UAvailable from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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