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EXPOSURE TO AN ORGANOPHOSPHATE (DFP) DURING A DEFINED PERIOD IN NEONATAL LIFE INDUCES PERMANENT CHANGES IN BRAIN MUSCARINIC RECEPTORS AND BEHAVIOR IN ADULT MICE
Uppsala University.
Uppsala University.
Uppsala University.
1995 (English)In: BRAIN RESEARCH, ISSN 0006-8993, Vol. 677, no 1, 13-19 p.Article in journal (Other scientific) Published
Abstract [en]

The organophosphate Diisopropylfluorophosphate (DFP) is a well-known inhibitor of cholinesterases. We have recently observed that neonatal exposure to a single subsymptomal dose of DFP induces permanent alterations in muscarinic cholinergic receptors (MAC

Place, publisher, year, edition, pages
ELSEVIER SCIENCE BV , 1995. Vol. 677, no 1, 13-19 p.
Keyword [en]
NEUROTOXICITY; NEONATAL; MUSCARINIC ACETYLCHOLINE RECEPTOR; BEHAVIOR; INSECTICIDE; ORGANOPHOSPHATE; DIISOPROPYLFLUOROPHOSPHATE; GROWTH CONE MOTILITY; SUPERIOR CERVICAL-GANGLION; NEURITE ELONGATION; MOUSE-BRAIN; COMPARATIVE TOXICITY; IDENTIFIED NEURONS; ME
Identifiers
URN: urn:nbn:se:uu:diva-85014OAI: oai:DiVA.org:uu-85014DiVA: diva2:112922
Note
Addresses: AHLBOM J, UPPSALA UNIV, DEPT ENVIRONM TOXICOL, NORBYVAGEN 18A, S-75236 UPPSALA, SWEDEN. UPPSALA UNIV, DEPT TOXICOL, S-75124 UPPSALA, SWEDEN.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-15

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