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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
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1998 (English)In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, Vol. 95, no 21, 12208-12213 p.Article in journal (Other scientific) Published
Abstract [en]

Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene expression of key metabolic enzymes, Here, a computational search approach based on iteratively built hidden Markov models of nuclea

Place, publisher, year, edition, pages
1998. Vol. 95, no 21, 12208-12213 p.
Keyword [en]
HIDDEN MARKOV-MODELS; PRIMARY CULTURES; BOVINE LIVER; FATTY-ACIDS; ACTIVATION; ALPHA; GENE; SUPERFAMILY; EXPRESSION; GAMMA
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URN: urn:nbn:se:uu:diva-85130PubMedID: 9770465OAI: oai:DiVA.org:uu-85130DiVA: diva2:113038
Note
Addresses: Berkenstam A, Pharmacia & Upjohn Inc, Dept Mol Biol & Genomics, S-11287 Stockholm, Sweden. Pharmacia & Upjohn Inc, Dept Mol Biol & Genomics, S-11287 Stockholm, Sweden. Pharmacia & Upjohn Inc, Dept Biochem & Cell Biol, S-11287 Stockholm, Sweden.Available from: 2007-02-12 Created: 2007-02-12 Last updated: 2011-01-14

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Ohlsson, R

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