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Low dose effects of chemicals as assessed by the flow cytometric in vivo micronucleus assay
Uppsala University.
Uppsala University.
Uppsala University.
1998 (English)In: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, ISSN 0027-5107, Vol. 405, no 2, 199-208 p.Article in journal (Other scientific) Published
Abstract [en]

Using flow cytometric automation of the mouse in vivo, micronucleus assay increases the sensitivity of the test. This is achieved through a very large increase in the number of cells scored, by a factor of 100 X, which in turn greatly reduces the sampling

Place, publisher, year, edition, pages
ELSEVIER SCIENCE BV , 1998. Vol. 405, no 2, 199-208 p.
Keyword [en]
micronucleus assay; flow cytometric automation; mouse; MOUSE PERIPHERAL-BLOOD; BONE-MARROW; POLYCHROMATIC ERYTHROCYTES; INTRAPERITONEAL INJECTION; MULTIPLE TREATMENTS; HUMAN-LYMPHOCYTES; SPINDLE POISONS; ACRIDINE-ORANGE; MITOMYCIN-C; ORAL GAVAGE
Identifiers
URN: urn:nbn:se:uu:diva-85131OAI: oai:DiVA.org:uu-85131DiVA: diva2:113039
Note
Addresses: Grawe J, Univ Stockholm, Wallenberg Lab, Dept Genet & Cellular Toxicol, S-10691 Stockholm, Sweden. Univ Stockholm, Wallenberg Lab, Dept Genet & Cellular Toxicol, S-10691 Stockholm, Sweden. Uppsala Univ, Dept Genet, S-75007 Uppsala, Sweden.Available from: 2008-10-17 Created: 2008-10-17 Last updated: 2011-01-14

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