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Genomewide analysis of admixture and adaptation in the Africanized honeybee
Uppsala University, Science for Life Laboratory, SciLifeLab. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. Uppsala University, Science for Life Laboratory, SciLifeLab.
Univ Sao Paulo, FFCLRP, Dept Biol, Ribeirao Preto, Brazil.;Univ Sao Paulo, FMRP, Dept Genet, Ribeirao Preto, Brazil..
Univ Bristol, Dept Math, Bristol, Avon, England..
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2017 (English)In: Molecular Ecology, ISSN 0962-1083, E-ISSN 1365-294X, Vol. 26, no 14, 3603-3617 p.Article in journal (Refereed) Published
Abstract [en]

Genetic exchange by hybridization or admixture can make an important contribution to evolution, and introgression of favourable alleles can facilitate adaptation to new environments. A small number of honeybees (Apis mellifera) with African ancestry were introduced to Brazil similar to 60 years ago, which dispersed and hybridized with existing managed populations of European origin, quickly spreading across much of the Americas in an example of a massive biological invasion. Here, we analyse whole-genome sequences of 32 Africanized honeybees sampled from throughout Brazil to study the effect of this process on genome diversity. By comparison with ancestral populations from Europe and Africa, we infer that these samples have 84% African ancestry, with the remainder from western European populations. However, this proportion varies across the genome and we identify signals of positive selection in regions with high European ancestry proportions. These observations are largely driven by one large gene-rich 1.4-Mbp segment on chromosome 11 where European haplotypes are present at a significantly elevated frequency and likely confer an adaptive advantage in the Africanized honeybee population. This region has previously been implicated in reproductive traits and foraging behaviour in worker bees. Finally, by analysing the distribution of ancestry tract lengths in the context of the known time of the admixture event, we are able to infer an average generation time of 2.0 years. Our analysis highlights the processes by which populations of mixed genetic ancestry form and adapt to new environments.

Place, publisher, year, edition, pages
2017. Vol. 26, no 14, 3603-3617 p.
Keyword [en]
adaptation, admixture, Africanized honeybee, biological invasion, introgression, natural selection
National Category
Evolutionary Biology Biochemistry and Molecular Biology Ecology
Identifiers
URN: urn:nbn:se:uu:diva-330033DOI: 10.1111/mec.14122ISI: 000404618000004OAI: oai:DiVA.org:uu-330033DiVA: diva2:1145574
Funder
Swedish Research Council, 2014-5096Swedish Research Council Formas, 2013-722Science for Life Laboratory - a national resource center for high-throughput molecular bioscience, 2014/R2-49Carl Tryggers foundation , CTS14:508
Available from: 2017-09-29 Created: 2017-09-29 Last updated: 2017-09-29Bibliographically approved

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Wallberg, AndreasWebster, Matthew Thomas

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