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Clinical and audiological short-term and long-term outcomes of fat graft myringoplasty
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland. Vasteras Hosp, Dept Otorhinolaryngol, Vasteras, Sweden.
Vasteras Hosp, Dept Otorhinolaryngol, Vasteras, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland. Vasteras Hosp, Dept Otorhinolaryngol, Vasteras, Sweden.; Akershus Univ Hosp, Dept Otorhinolaryngol, Oslo, Norway.;Univ Oslo, Oslo, Norway..
2017 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 137, no 9, 940-944 p.Article in journal (Refereed) Published
Abstract [en]

Introduction: Results of fat graft myringoplasty are often reported with only short-term follow-up. Audiological results are less commonly reported, as well as long-term follow-up results. Materials and methods: One hundred consecutive patients scheduled for fat graft myringoplasty were included in a prospective cohort study. Clinical and audiological outcomes were assessed at six weeks and one year postoperatively. Results: Perforation sizes ranged from 0.5 to 4 mm. The six-week follow-up showed a total perforation closure rate of 72.9% with a statistically significant (p = .03) higher rate for the pediatric age group (83.0%). 64.4% of all patients were healed at one-year follow-up. Statistical analyses for background factors did not reveal any significant difference in healing rates with regard to patient sex or location or cause of the perforation. The mean preoperative air-conduction (AC) threshold was 25dB with an air-bone gap of 12 dB. At the one-year follow-up the mean air conduction threshold for healed ears was improved to 16.6 dB, still 54.2% of them had a type B tympanogram. Conclusions: Children had a higher perforation closure rate at six-week follow-up than adult patients. Recurrent tympanic membrane perforations were common after initially successful fat graft myringoplasties. Long-term hearing was improved after successful fat graft myringoplasty, resulting in a mean AC threshold of 16.6 dB.

Place, publisher, year, edition, pages
2017. Vol. 137, no 9, 940-944 p.
Keyword [en]
Tympanic membrane perforation, fat graft myringoplasty, pediatric patients, audiometry, tympanometry, healing result
National Category
Otorhinolaryngology
Identifiers
URN: urn:nbn:se:uu:diva-331903DOI: 10.1080/00016489.2017.1326063ISI: 000405304900007PubMedID: 28537107OAI: oai:DiVA.org:uu-331903DiVA: diva2:1152286
Available from: 2017-10-24 Created: 2017-10-24 Last updated: 2017-10-24Bibliographically approved

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Knutsson, Johanvon Unge, Magnus

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