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On the relationship between epistasis and genetic variance heterogeneity.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. (Carlborg)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology. (Carlborg)ORCID iD: 0000-0002-2722-5264
2017 (English)In: Journal of Experimental Botany, ISSN 0022-0957, E-ISSN 1460-2431Article in journal (Refereed) Epub ahead of print
Abstract [en]

Epistasis and genetic variance heterogeneity are two non-additive genetic inheritance patterns that are often, but not always, related. Here we use theoretical examples and empirical results from earlier analyses of experimental data to illustrate the connection between the two. This includes an introduction to the relationship between epistatic gene action, statistical epistasis, and genetic variance heterogeneity, and a brief discussion about how genetic processes other than epistasis can also give rise to genetic variance heterogeneity.

Place, publisher, year, edition, pages
2017.
Keyword [en]
Epistasis, gene action, genetic variance heterogeneity, genotype–phenotype maps, non-additive, quantitative genetics
National Category
Genetics
Identifiers
URN: urn:nbn:se:uu:diva-332732DOI: 10.1093/jxb/erx283PubMedID: 28992256OAI: oai:DiVA.org:uu-332732DiVA: diva2:1153928
Available from: 2017-11-01 Created: 2017-11-01 Last updated: 2017-11-01

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