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Physical activity and the risk of hip fracture in the elderly: a prospective cohort study
Karolinska Univ Hosp, Clin Epidemiol Unit T2, Dept Med, S-17176 Stockholm, Sweden.; Karolinska Univ Hosp, Dept Med Clin Endocrinol Metab & Diabet, C2 84, S-14186 Stockholm, Sweden.
Univ Milano Bicocca, Dept Stat & Quantitat Methods, Edificio U7,Via Bicocca Arcimboldi 8, I-20126 Milan, Italy.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, UCR-Uppsala Clinical Research Center.ORCID iD: 0000-0003-2815-1217
Karolinska Inst, Dept Med Epidemiol & Biostat, POB 281, S-17177 Stockholm, Sweden.
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2017 (English)In: European Journal of Epidemiology, ISSN 0393-2990, E-ISSN 1573-7284, Vol. 32, no 11, p. 983-991Article in journal (Refereed) Published
Abstract [en]

Physical activity has been inversely associated with the risk of hip fracture, however, few studies have been conducted on the contributions from different domains of physical activity. This study was performed to investigate the association between daily household activities, leisure time physical activity, work-related physical activity and total physical activity during a 24-h period, and the risk of hip fracture. In the Swedish National March Cohort we followed 23,881 men and women aged of 50 and over from 1997 until 2010. Information on domain-specific physical activity was collected at baseline using a questionnaire. We fitted separate multivariable adjusted Cox proportional hazard models to each domain to obtain hazard ratios (HRs) with 95% confidence intervals (CIs). Each model was mutually adjusted for the other domains of physical activity. During a mean follow-up period of 12.2 years we identified 824 incidents of hip fracture. Subjects who spent less than 1 h per week engaged in daily household activities had an 85% higher risk of hip fracture than subjects spending ≥6 h per week carrying out daily household activities (HR 1.85; 95% CI 1.01-3.38). Subjects engaged in leisure time physical activities for >3.1 MET-h/day had a 24% lower risk of hip fracture (HR 0.76; 95% CI 0.59-0.98) than subjects spending <1.1 MET-h/day performing such activities. No association was found between hip fracture and work-related or total physical activity. We conclude that daily household activities and leisure time physical activity may independently decrease the risk of hip fracture in those aged 50 and over.

Place, publisher, year, edition, pages
2017. Vol. 32, no 11, p. 983-991
Keyword [en]
Epidemiology, Exercise, Hip fractures, Risk factors
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
URN: urn:nbn:se:uu:diva-334455DOI: 10.1007/s10654-017-0312-5ISI: 000415124400005PubMedID: 28940092OAI: oai:DiVA.org:uu-334455DiVA, id: diva2:1159645
Funder
Swedish Cancer Society, CAN 2012/591
Available from: 2017-11-23 Created: 2017-11-23 Last updated: 2018-02-23Bibliographically approved

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Michaëlsson, Karl

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