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European Respiratory Society guidelines for the management of adult bronchiectasis
Univ Barcelona, Hosp Univ Vall dHebron HUVH, Inst Recerca Vall dHebron VHIR,CIBERES, Hosp Clin Barcelona,Fdn Clin,Serv Pneumol,IDIBAPS, Barcelona, Spain..
AZ Nikolaas, Dept Resp Med, St Niklaas, Belgium.;UZ Leuven, Dept Resp Med, Leuven, Belgium..
Galway Univ Hosp, Dept Resp Med, Galway, Ireland.;Natl Univ Ireland, Lung Biol Grp, Galway, Ireland.;Newcastle Univ, Inst Cell & Mol Biol, Newcastle Upon Tyne, Tyne & Wear, England..
Univ Milan, Dept Pathophysiol & Transplantat, Dept Internal Med, Resp Unit, Milan, Italy.;Fdn IRCCS Ca Granda Osped Maggiore Policlin Milan, Adult Cyst Fibrosis Ctr, Milan, Italy..
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2017 (English)In: European Respiratory Journal, ISSN 0903-1936, E-ISSN 1399-3003, Vol. 50, no 3, article id 1700629Article in journal (Refereed) Published
Abstract [en]

Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines. The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature. A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy. These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.

Place, publisher, year, edition, pages
EUROPEAN RESPIRATORY SOC JOURNALS LTD , 2017. Vol. 50, no 3, article id 1700629
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Respiratory Medicine and Allergy
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URN: urn:nbn:se:uu:diva-335407DOI: 10.1183/13993003.00629-2017ISI: 000410089300014OAI: oai:DiVA.org:uu-335407DiVA, id: diva2:1163117
Available from: 2017-12-06 Created: 2017-12-06 Last updated: 2017-12-06Bibliographically approved

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Ställberg, Björn

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