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Alcohol consumption and risk of heart failure: Meta-analysis of 13 prospective studies.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Orthopaedics.
2017 (English)In: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, S0261-5614(17)30168-1Article in journal (Refereed) Epub ahead of print
Abstract [en]

BACKGROUND & AIMS: Controversy exists on the association between alcohol consumption and risk of heart failure (HF). We carried out a meta-analysis to summarize available prospective data on alcohol consumption and HF.

METHODS: We searched PubMed for relevant studies published until January 1, 2017. Relative risk (RR) estimates from individual studies were pooled in a random-effects meta-analysis.

RESULTS: A total of 13 prospective studies, with 13,738 HF cases and 355,804 participants, were included in the meta-analysis. Light alcohol drinking (0.1-7 drinks/week) was inversely associated with risk of HF (RR, 0.86; 95% confidence interval, 0.81-0.90). There was no statistically significant association between moderate (7.1-14 drinks/week), high (14.1-28 drinks/week), or heavy (>28 drinks/week) alcohol consumption and HF risk. Former drinking was associated with an increased risk of HF compared with never or occasional drinking (RR, 1.22; 95% confidence interval, 1.11-1.33).

CONCLUSIONS: This meta-analysis found that light alcohol drinking was associated with a lower risk of HF. Former drinking was associated with a higher risk of HF.

Place, publisher, year, edition, pages
2017. S0261-5614(17)30168-1
Keyword [en]
Alcohol consumption, Heart failure, Meta-analysis, Prospective studies
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-337265DOI: 10.1016/j.clnu.2017.05.007PubMedID: 28554815OAI: oai:DiVA.org:uu-337265DiVA: diva2:1168702
Available from: 2017-12-21 Created: 2017-12-21 Last updated: 2017-12-21

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