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Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Molecular epidemiology.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Molecular epidemiology.
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2017 (English)In: Scandinavian Journal of Clinical and Laboratory Investigation, ISSN 0036-5513, E-ISSN 1502-7686, 1-5 p.Article in journal (Refereed) Epub ahead of print
Abstract [en]

Faecal calprotectin is a protein used as a diagnostic marker for inflammatory bowel diseases. We determined upper limits for normal calprotectin values for neonatal, 6, 12 and 24 months old children using a turbidimetric immunoassay in a cohort of Swedish children. The advantage of the method is that opposite to previously used enzyme-linked immunosorbent assay (ELISA) method, it enables measuring single samples, and thus, shortens the analysis time significantly. There were 72 samples (41.7% female) collected neonatally, 63 samples (34.9% female) at 6 months, 60 samples (40.0% female) at 12 months and 51 samples (43.1% female) at 24 months. The upper limits for normal values were 233, 615, 136 and 57 µg mg-1 for infants aged 0, 6, 12 and 24 months, respectively.

Place, publisher, year, edition, pages
2017. 1-5 p.
Keyword [en]
Calprotectin, abdominal pain, inflammatory bowel disease, normal values, turbidimetric immunoassay
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:uu:diva-337523DOI: 10.1080/00365513.2017.1420216PubMedID: 29283308OAI: oai:DiVA.org:uu-337523DiVA: diva2:1169901
Available from: 2017-12-30 Created: 2017-12-30 Last updated: 2017-12-30

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