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ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Peptide Receptor Radionuclide Therapy with Radiolabelled Somatostatin Analogues
Peter MacCallum Canc Ctr, Canc Imaging & Neuroendocrine Serv, 305 Grattan St.ORCID iD: 0000-0002-0758-0824
Erasmus MC, ENETS Ctr Excellence Rotterdam, Div Nucl Med, Dept Internal Med.
Erasmus MC, Cyclotron Rotterdam BV.
Mem Sloan Kettering Canc Ctr.
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2017 (English)In: Neuroendocrinology, ISSN 0028-3835, E-ISSN 1423-0194, Vol. 105, no 3, p. 295-309Article in journal (Refereed) Published
Abstract [en]

The purpose of these guidelines is to assist physicians caring for patients with neuroendocrine neoplasia in considering eligibility criteria for peptide receptor radionuclide therapy (PRRT) and in defining the minimum requirements for PRRT. It is not these guidelines' aim to give recommendations on the use of specific radiolabelled somatostatin analogues for PRRT as different analogues are being used, and their availability is governed by varying international regulations. However, a recent randomized controlled trial, NETTER-1, has provided evidence that may establish Lu-177-DOTA-octreotate (LutaThera (R)) as the first widely approved agent. It also makes recommendations on what minimal patient, tumour, and treatment outcome characteristics should be reported for PRRT to facilitate robust comparisons between studies.

Place, publisher, year, edition, pages
KARGER , 2017. Vol. 105, no 3, p. 295-309
Keyword [en]
Radiolabelled somatostatin analogues, Gastroenteropancreatic neuroendocrine tumour, Neuroendocrine tumour, Peptide receptor radionuclide therapy
National Category
Neurosciences Endocrinology and Diabetes
Identifiers
URN: urn:nbn:se:uu:diva-336665DOI: 10.1159/000475526ISI: 000411501200009PubMedID: 28402980OAI: oai:DiVA.org:uu-336665DiVA, id: diva2:1170813
Available from: 2018-01-04 Created: 2018-01-04 Last updated: 2018-01-13Bibliographically approved

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