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Attention-deficit/hyperactivity disorder and physical multimorbidity: A population-based study
NCNP, Dept Child & Adolescent Mental Hlth, Natl Inst Mental Hlth, 4-1-1 Ogawahigashi, Kodaira, Tokyo 1878553, Japan.;Sodertorn Univ, Stockholm Ctr Hlth & Social Change SCOHOST, S-14189 Huddinge, Sweden.;Univ Tokyo, Grad Sch Med, Dept Human Ecol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan..
Univ Barcelona, Fundacio St Joan de Deu, Parc Sanitari St Joan de Deu, Dr Antoni Pujadas 42, Barcelona 08830, Spain.;CIBERSAM, Inst Salud Carlos III, Ctr Invest Biomed Red Salud Mental, Monforte de Lemos 3-5 Pabellon 11, Madrid 28029, Spain..
NCNP, Dept Child & Adolescent Mental Hlth, Natl Inst Mental Hlth, 4-1-1 Ogawahigashi, Kodaira, Tokyo 1878553, Japan..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Child and Adolescent Psychiatry. Yale Univ, Sch Med, Ctr Child Study, 333 Cedar St, New Haven, CT 06520 USA.
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2017 (English)In: European psychiatry, ISSN 0924-9338, E-ISSN 1778-3585, Vol. 45, p. 227-234Article in journal (Refereed) Published
Abstract [en]

Background: There has been little research on the association of attention-deficit/hyperactivity disorder (ADHD) with co-occurring physical diseases. The aim of this study was to examine the association between possible ADHD and physical multimorbidity (i.e. >= 2 physical diseases) among adults in the English general population.

Methods: Data were analyzed from 7274 individuals aged >= 18 years that came from the Adult Psychiatric Morbidity Survey 2007. ADHD symptoms were assessed with the Adult Self-Report Scale (ASRS) Screener. Information was also obtained on 20 self-reported doctor/other health professional diagnosed physical health conditions present in the past 12 months. Multivariable logistic regression and mediation analyses were conducted to assess the associations.

Results: There was a monotonic relation between the number of physical diseases and possible ADHD (ASRS score >= 14). Compared to those with no diseases, individuals with >= 5 diseases had over 3 times higher odds for possible ADHD (odds ratio [OR]: 3.30, 95% confidence interval [CI]: 2.48-4.37). This association was observed in all age groups. Stressful life events (% mediated 10.3-24.3%), disordered eating (6.8%), depression (12.8%), and anxiety (24.8%) were significant mediators in the association between possible ADHD and physical multimorbidity.

Conclusion: Adults that screen positive for ADHD are at an increased risk for multimorbidity and several factors are important in this association. As many adults with ADHD remain undiagnosed, the results of this study highlight the importance of detecting adult ADHD as it may confer an increased risk for poorer health outcomes, including physical multimorbidity.

Place, publisher, year, edition, pages
2017. Vol. 45, p. 227-234
Keywords [en]
ADHD, Multimorbidity, Physical disease, Epidemiology, Stress
National Category
Psychiatry
Identifiers
URN: urn:nbn:se:uu:diva-341632DOI: 10.1016/j.eurpsy.2017.07.010ISI: 000414461300032PubMedID: 28957792OAI: oai:DiVA.org:uu-341632DiVA, id: diva2:1182030
Available from: 2018-02-12 Created: 2018-02-12 Last updated: 2018-02-12Bibliographically approved

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Ruchkin, Vladislav V.

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