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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics-Guided Warfarin Dosing: 2017 Update
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2017 (English)In: Clinical Pharmacology and Therapeutics, ISSN 0009-9236, E-ISSN 1532-6535, Vol. 102, no 3, p. 397-404Article, review/survey (Refereed) Published
Abstract [en]

This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for CYP2C9, VKORC1, CYP4F2, and rs12777823 genotype-guided warfarin dosing to achieve a target international normalized ratio of 2-3 when clinical genotype results are available. In addition, this updated guideline incorporates recommendations for adult and pediatric patients that are specific to continental ancestry.

Place, publisher, year, edition, pages
2017. Vol. 102, no 3, p. 397-404
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Clinical Laboratory Medicine
Identifiers
URN: urn:nbn:se:uu:diva-342581DOI: 10.1002/cpt.668ISI: 000407082400015OAI: oai:DiVA.org:uu-342581DiVA, id: diva2:1184894
Funder
Swedish Research Council, 521-2011-2440Swedish Research Council, 521-2014-3370Swedish Heart Lung Foundation, 20120557Swedish Heart Lung Foundation, 20140291Available from: 2018-02-22 Created: 2018-02-22 Last updated: 2018-04-05Bibliographically approved

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Wadelius, Mia

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