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Antiplatelet Agents for the Treatment and Prevention of Coronary Atherothrombosis
Catholic Univ, Sch Med, Dept Pharmacol, Largo F Vito 1, I-00168 Rome, Italy..
Santo Andres Hosp, Div Cardiol, Leiria, Portugal..
Univ Oxford, Nuffield Dept Populat Hlth, MRC Populat Hlth Res Unit, Oxford, England..
Sorbonne Univ Paris 6, Hop Pitie Salpetriere, APHP, ACT Study Grp,Inst Cardiol,INSERM,UMRS 1166, Paris, France..
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2017 (English)In: Journal of the American College of Cardiology, ISSN 0735-1097, E-ISSN 1558-3597, Vol. 70, no 14, p. 1760-1776Article, review/survey (Refereed) Published
Abstract [en]

Antiplatelet drugs provide first-line antithrombotic therapy for the management of acute ischemic syndromes (both coronary and cerebrovascular) and for the prevention of their recurrence. Their role in the primary prevention of atherothrombosis remains controversial because of the uncertain balance of the potential benefits and risks when combined with other preventive strategies. The aim of this consensus document is to review the evidence for the efficacy and safety of antiplatelet drugs, and to provide practicing cardiologists with an updated instrument to guide their choice of the most appropriate antiplatelet strategy for the individual patient presenting with different clinical manifestations of coronary atherothrombosis, in light of comorbidities and/or interventional procedures.

Place, publisher, year, edition, pages
2017. Vol. 70, no 14, p. 1760-1776
Keywords [en]
aspirin, cangrelor, clopidogrel, prasugrel, ticagrelor, vorapaxar
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:uu:diva-346542DOI: 10.1016/j.jacc.2017.08.037ISI: 000411615300011PubMedID: 28958334OAI: oai:DiVA.org:uu-346542DiVA, id: diva2:1192036
Available from: 2018-03-21 Created: 2018-03-21 Last updated: 2018-03-21Bibliographically approved

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Siegbahn, Agneta

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