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Adult onset and remission of respiratory symptoms, asthma and rhinitis in relation to dampness, mould and mould odour: the RHINE cohort
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Occupational and Environmental Medicine.
Institute of Family Medicine and Public Health, University of Tartu, Estonia..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
Lung Clinic, Tartu University Hospital, Tartu, Estonia..
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(English)In: Article in journal (Other academic) Submitted
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-347692OAI: oai:DiVA.org:uu-347692DiVA, id: diva2:1195663
Available from: 2018-04-06 Created: 2018-04-06 Last updated: 2018-04-06
In thesis
1. Asthma and Rhinitis among Adults in Sweden and China: Risk Factors in the Home Environment
Open this publication in new window or tab >>Asthma and Rhinitis among Adults in Sweden and China: Risk Factors in the Home Environment
2018 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The main aim of this thesis was to evaluate associations between selected home environment factors and asthma, rhinitis and respiratory symptoms among adults from Sweden, China and northern Europe. Two studies were performed in Sweden, one in China, and one longitudinal cohort study was performed in northern Europe. Dampness/mould was common, and was a main risk factor in all studies. Other risk factors for asthma symptoms in Sweden included window pane condensation in winter, multi-family buildings constructed from 1961-1975, rented apartments, environment tobacco smoke (ETS), and living in a colder climate zone. Higher ventilation flow in Sweden was associated with less asthma symptoms. Risk factors for rhinitis in Sweden included window pane condensation, a higher moisture load, concrete slab foundation constructed before 1991, multi-family buildings constructed from 1976-1985, rented apartments and living in densely populated areas. Risk factors for rhinitis in China included window pane condensation, recent redecoration, new furniture, presence of cockroaches, pet keeping, ETS and living near a main road or highway. Frequently cleaning of the home and putting beddings to sunshine were protective factors for rhinitis in China. Other risk factors for respiratory infections in Sweden included houses with a brick façade, window pane condensation, a higher moisture load, multi-family buildings constructed from 1976-1985, rented apartments and living in densely populated areas. Furthermore, dampness and mould, and mould odour were risk factors for onset of asthma and rhinitis in northern Europe. In conclusion, indoor dampness and mould can be a risk factor for asthma and rhinitis in Sweden, China and northern Europe. Certain construction years (1961-1985), ETS, recent redecoration, new furniture, living in urban areas and exposure to traffic air pollution can be risk factors for asthma, rhinitis or respiratory infections. A high ventilation flow and daily cleaning at home can be protective.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2018. p. 80
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 1467
Keywords
Rhinitis, Asthma, Home, Dampness, Mould, Ventilation
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Research subject
Occupational and Environmental Medicine
Identifiers
urn:nbn:se:uu:diva-347698 (URN)978-91-513-0347-5 (ISBN)
Public defence
2018-06-12, Konferensrummet, Arbets- och miljömedicin, Daghammarskjölds väg 60, Uppsala, 09:00 (English)
Opponent
Supervisors
Available from: 2018-05-21 Created: 2018-04-06 Last updated: 2018-05-21

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