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Nutrition supplements when undergoing orthopedic surgery
2014 (English)Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Malnutrition is prevalent in elderly populations with orthopedic disabilities, which is especially critical during surgery when the body is under much stress. It is important that these patients are well nourished to be able to cope when mechanisms such as immune system are activated. Nutrition is also important after surgery when the body is healing and sometimes struggling against different complications as infections. The aim of this study was to evaluate if nutrition supplements decreases the time needed for rehabilitation and improve the outcome after orthopedic surgeries. This was performed by analyzing biomarkers involved in wound healing. The study population comprised of 100 surgical patients at the age of 50 or older. The participant where divided into two groups, one test group that received nutrition supplements and one control group who did not receive any extra nutrition. Sandwich ELISA was used to measure myostatin, cathepsin S and cathepsin B concentrations in patient serum before and after surgery. There were no significant difference between the control group and the test group for any of the three biomarkers. The conclusion is that nutrition supplement does not decrease the rehabilitation time and outcome according to the results in this study.

Place, publisher, year, edition, pages
2014.
Keywords [en]
fracture, mendelsons syndrome, nutrition intervention, Myostatin, Cathepsin S, Cathepsin B
National Category
Biomedical Laboratory Science/Technology
Identifiers
URN: urn:nbn:se:uu:diva-349257OAI: oai:DiVA.org:uu-349257DiVA, id: diva2:1201003
Educational program
Biomedical Laboratory Science Programme; Biomedical Laboratory Science Programme
Examiners
Available from: 2018-04-24 Created: 2018-04-24 Last updated: 2018-04-24Bibliographically approved

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