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Cellulose-based Nanocarriers as Platforms for Cancer Therapy
Beijing Forestry Univ, Coll Mat Sci & Technol, Beijing Key Lab Lignocellulos Chem, Engn Res Ctr Forestry Biomass Mat & Bioenergy, Beijing 100083, Peoples R China..
Beijing Forestry Univ, Coll Mat Sci & Technol, Beijing Key Lab Lignocellulos Chem, Engn Res Ctr Forestry Biomass Mat & Bioenergy, Beijing 100083, Peoples R China..
Beijing Forestry Univ, Coll Mat Sci & Technol, Beijing Key Lab Lignocellulos Chem, Engn Res Ctr Forestry Biomass Mat & Bioenergy, Beijing 100083, Peoples R China.;Qilu Univ Technol, Minist Educ Shandong Prov, Key Lab Pulp & Paper Sci & Technol, Jinan 250353, Shandong, Peoples R China..
Uppsala University, Disciplinary Domain of Science and Technology, Chemistry, Department of Chemistry - Ångström, Structural Chemistry.ORCID iD: 0000-0002-6326-8106
2017 (English)In: Current pharmaceutical design, ISSN 1381-6128, E-ISSN 1873-4286, Vol. 23, no 35, p. 5292-5300Article, review/survey (Refereed) Published
Abstract [en]

Cellulose is an important environmentally-friendly renewable polymer on the earth. Cellulose has been widely used as feedstocks for the synthesis of biomaterials, biofuels and biochemicals. Recently, cellulose and cellulose derivatives have received intense attention in biomedical applications, such as tissue engineering, scaffold, artificial blood vessel, skin grafts, artificial skin, drug carrier, and chronic skin diseases, many of which are somehow related to cancer therapy. In this mini-review, we focus on the up-to-date development of cellulose-based nanocarriers used for cancer therapy. Various cellulose-based nanocarriers such as bacterial cellulose (BC), cellulose acetate, microcrystalline cellulose, carboxymethyl cellulose, cellulose nanocrystals, cellulose nanofibrills, etc, are reviewed in terms of being used in drug delivery systems for cancer treatment. Different strategies for the synthesis of cellulose-based nanocarriers are summarized. Special attention is paid on the structure and properties of cellulose-based drug carriers for cancer therapy via some representative examples. Finally, the problems and future developments of these promising polymeric nanocarriers are raised and proposed.

Place, publisher, year, edition, pages
BENTHAM SCIENCE PUBL LTD , 2017. Vol. 23, no 35, p. 5292-5300
Keywords [en]
Cellulose, nanocarriers, platforms, cancer therapy, biomedical applications, tissue engineering
National Category
Cancer and Oncology Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-350125DOI: 10.2174/1381612823666171031111950ISI: 000423532100008PubMedID: 29086678OAI: oai:DiVA.org:uu-350125DiVA, id: diva2:1204208
Available from: 2018-05-07 Created: 2018-05-07 Last updated: 2018-05-07Bibliographically approved

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Zhu, Jie-Fang

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