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Psychiatric disorders in women and men up to five years after undergoing assisted reproductive technology treatment: a prospective cohort study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.ORCID iD: 0000-0003-0180-0280
Department of Public Health, University of Copenhagen, Denmark.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.ORCID iD: 0000-0003-4729-9962
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Psychiatry, University Hospital.
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2018 (English)In: Human Fertility, ISSN 1464-7273, E-ISSN 1742-8149, p. 1-6Article in journal (Refereed) Epub ahead of print
Abstract [en]

This is a prospective cohort study with the objective to describe psychiatric disorders, such as any mood and anxiety disorders, in both women and men five years after assisted reproductive technology (ART). The Primary Care Evaluation of Mental Disorders (PRIME-MD) questionnaire, based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), was used as the diagnostic tool to evaluate psychiatric disorders. Logistic regression analysis was used to calculate odds ratios (ORs) and confidence interval (CI) for factors associated with psychiatric disorders at the follow-up. Overall, 278 (63.3%) women and 183 (41.7%) men filled in and returned the questionnaire. Approximately 11.5% of women and 5.5% of men fulfilled the criteria for any psychiatric diagnosis. Of these, any mood disorder was present in 9.4% of women and 4.4% of men. The major risk factor for mood or anxiety disorders at follow-up was mood or anxiety disorders at the time of the index ART. Mood disorders were not more common in women who remained childless after ART. In conclusion, these findings indicate that psychiatric disorders at five years follow-up after ART are less common than at the baseline assessment in conjunction with the ART.

Place, publisher, year, edition, pages
2018. p. 1-6
Keywords [en]
Assisted reproductive technology, cohort study, depression, follow-up, infertility, psychiatric disorders
National Category
Psychiatry Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:uu:diva-351123DOI: 10.1080/14647273.2018.1474279PubMedID: 29768933OAI: oai:DiVA.org:uu-351123DiVA, id: diva2:1208751
Available from: 2018-05-19 Created: 2018-05-19 Last updated: 2018-09-12Bibliographically approved

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Volgsten, HelenaSkoog Svanberg, AgnetaEkselius, LSundström Poromaa, Inger

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Volgsten, HelenaSkoog Svanberg, AgnetaEkselius, LSundström Poromaa, Inger
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Department of Women's and Children's HealthPsychiatry, University HospitalReproductive Health
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Human Fertility
PsychiatryObstetrics, Gynecology and Reproductive Medicine

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