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Asthma and Sleep Disruption in Australia: A Retrospective Case-Control Study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences. The University of Sydney.
2018 (English)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction: Experiencing poor sleep quality has been demonstrated to negatively impact quality of life. Trends indicate a bidirectional link between sleep health and asthma, suggesting that poor asthma control may lead to poor sleep health, and that in turn poor sleep quality causes increased asthmatic morbidity and mortality. Aim: To quantitatively assess the association between insomnia and asthma in a population survey. Materials and Methods: The sample included Australians aged 18+ years who participated in an online survey (Big Sleep Survey) about sleep habits and sociodemographic risk factors, as well as completed an optional seven-day sleep diary. Using validated measures such as the Insomnia Severity Index, the Epworth Sleepiness Scale and Sleep Diary data, insomnia symptoms were then examined among survey participants with asthma and matched non-asthma controls. Independent t-test, Pearson’s chi-squared test and linear mixed-effect modelling were used to test the difference between the two groups with a significance level of 5%. For significantly different findings, the effect size was then evaluated using Cohen’s d and Cramer’s V respectively. Results: Data were analysed from 512 cases and 512 controls (70% female), of which 157 cases and 157 controls completed the sleep diary. People with asthma scored significantly higher than controls on the ISS and the ESS (p-values <0.001 and 0.029). People with asthma also demonstrated a significantly poorer sleep quality (p-value 0.015) and a trend towards longer sleep onset latency than the controls. Conclusion: Australians with asthma experience subjectively poorer sleep quality and have a higher frequency of insomnia symptoms than Australians without asthma.

Place, publisher, year, edition, pages
2018.
Keywords [en]
asthma, sleep, insomnia, quantitative study, insomnia severity index, epworth sleepiness scale, sleep diary
National Category
Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-353076OAI: oai:DiVA.org:uu-353076DiVA, id: diva2:1215975
External cooperation
The University of Sydney; Woolcock Institute of Medical Research
Subject / course
Pharmacotherapy
Educational program
Master of Science Programme in Pharmacy
Supervisors
Examiners
Available from: 2018-06-11 Created: 2018-06-10 Last updated: 2018-06-11Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
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More languages
Output format
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  • asciidoc
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