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Intervention delivery within the MedBridgestudy: a substudy analysing drug discrepancies, drug-related problems andpharmacist proposals
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Biosciences.
2018 (English)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Background: The Medication Reviews Bridging Healthcare (MedBridge) study is a multicentre, cluster-randomised, crossover trial to investigate the effects of comprehensive medication reviews (CMRs) performed in hospitals on elderly patients with and without active follow-up compared to usual care. The intervention delivery, the degree to which an intervention is being delivered, is essential for understanding the results of a clinical study involving complex interventions, such as CMRs. Aim: The aim of this substudy was to assess the intervention delivery within the MedBridge study in terms of identified drug discrepancies, drug-related problems (DRPs) and pharmacist proposals within the CMRs. Materials and methods: Every second study patient, that had received a CMR during an eight-week period at the six study wards in Uppsala, Enköping and Gävle, was included. Written notes and the medication lists in the patients’ medical record were analysed to identify and classify drug discrepancies, DRPs and pharmacist proposals. Correction rates for discrepancies and acceptance rates for pharmacist proposals were estimated using proportions. Results: The CMRs of 141 patients, with an average age of 80.5 years and 9.3 prescribed medications, were analysed. A mean of 1.2 discrepancies and 2.4 DRPs were identified. The most frequent DRP was "Other improper medication selection" and the most frequent pharmacist proposal was "Medication monitoring". The correction rate of discrepancies was 77% and the acceptance rate of pharmacist proposals was 71%. Conclusions: The interventions in terms of identified discrepancies, DRPs and pharmacist proposals within the CMRs seemed to be well-delivered and comparable to previous studies.

Place, publisher, year, edition, pages
2018.
Keywords [en]
MedBridge, DRP, discrepancy, drug-related problem, clinical charmacist, pharmacist proposals
National Category
Pharmaceutical Sciences
Identifiers
URN: urn:nbn:se:uu:diva-354084OAI: oai:DiVA.org:uu-354084DiVA, id: diva2:1220632
Subject / course
Pharmacotherapy
Educational program
Master of Science Programme in Pharmacy
Supervisors
Examiners
Available from: 2018-06-20 Created: 2018-06-19 Last updated: 2018-06-20Bibliographically approved

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CiteExportLink to record
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Citation style
  • apa
  • ieee
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Language
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Output format
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