uu.seUppsala University Publications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Effects of acute antihistamine exposure on thermal tolerance and behaviour in the freshwater snail, Planorbarius corneus
(English)Manuscript (preprint) (Other academic)
Abstract [en]

Antihistamine pollutants have the potential to interfere with the normal functioning of aquatic organisms due to their intentionally bio-active nature. Histamine is a neurotransmitter present in multiple tissues in both vertebrates and invertebrates and histaminergic pathways have been identified in the thermoregulatory processes of invertebrates. Disruption of normal histamine functioning via exposure to the widespread antihistamine pollution observed in fresh waters may induce a range of sub-lethal effects on aquatic invertebrates including thermoregulatory and behavioural changes. We conducted three experiments exposing freshwater snails (Planorbarius corneus) to the antihistamine, diphenhydramine, for 24 hours then evaluating thermal tolerance, temperature preference and righting time. Diphenhydramine was found to increase thermal tolerance and righting time, but did not affect temperature preference. These results warrant further investigation into the biological effects of antihistamines on aquatic wildlife as well as altered thermal tolerance and thermoregulation as relevant toxicological endpoints in ecotoxicological risk assessment of pharmaceuticals.

National Category
Biological Sciences
Identifiers
URN: urn:nbn:se:uu:diva-354696OAI: oai:DiVA.org:uu-354696DiVA, id: diva2:1222299
Available from: 2018-06-21 Created: 2018-06-21 Last updated: 2018-06-27
In thesis
1.
The record could not be found. The reason may be that the record is no longer available or you may have typed in a wrong id in the address field.

Open Access in DiVA

No full text in DiVA

Biological Sciences

Search outside of DiVA

GoogleGoogle Scholar

urn-nbn

Altmetric score

urn-nbn
Total: 2 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf