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Systematic misclassification of gestational age by ultrasound biometry: implications for clinical practice and research methodology in the Nordic countries
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Obstetrics and Reproductive Health Research.ORCID iD: 0000-0002-4935-7532
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Obstetrics and Reproductive Health Research. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Centre for Clinical Research, County of Västmanland.ORCID iD: 0000-0003-3603-7983
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Research group (Dept. of women´s and children´s health), Obstetrics and Reproductive Health Research.ORCID iD: 0000-0003-3507-3659
Karolinska Inst, Ctr Pharmacoepidemiol, Dept Med, Solna, Sweden.
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2018 (English)In: Acta Obstetricia et Gynecologica Scandinavica, ISSN 0001-6349, E-ISSN 1600-0412, Vol. 97, no 4, p. 440-444Article in journal, Editorial material (Other academic) Published
Abstract [en]

Historically, pregnancy dating has been based on self-reported information on the first day of the last menstrual period. In the 1970s, ultrasound biometry was introduced as an alternative for pregnancy dating and is now the leading method in Nordic countries. The use of ultrasound led to a reduction of post-term births and fewer inductions, and is considered more precise than last menstrual period-based methods for pregnancy dating. Nevertheless, differences in early growth and specific situations, such as maternal obesity, can render its estimates less precise, leading to gestational age misclassification. Clinical implications of ultrasound dating include effect on timely induction in case of post-term pregnancies, treatment with corticosteroids in cases of anticipated preterm delivery and decision on viability in cases of extreme prematurity. Furthermore, gestational age misclassification may influence the numbers and the magnitude of some adverse perinatal outcomes, closely related to gestational age, which are recorded in the Nordic birth registers.

Place, publisher, year, edition, pages
2018. Vol. 97, no 4, p. 440-444
Keywords [en]
Pregnancy dating, ultrasound biometry, last menstrual period, gestational age misclassification, Nordic countries
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:uu:diva-355820DOI: 10.1111/aogs.13300ISI: 000427561800011PubMedID: 29352467OAI: oai:DiVA.org:uu-355820DiVA, id: diva2:1231369
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Special Issue: SI

Available from: 2018-07-06 Created: 2018-07-06 Last updated: 2018-07-19Bibliographically approved

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Skalkidou, AlkistisKullinger, MeritGeorgakis, Marios K.

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Obstetrics and Reproductive Health ResearchCentre for Clinical Research, County of Västmanland
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