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Insight into β-Hairpin Stability: Interstrand Hydrogen Bonding
(organisk kemi)ORCID iD: 0000-0003-0359-5970
2013 (English)In: Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, ISSN 0936-5214, E-ISSN 1437-2096, Vol. 24, p. 2407-2410Article in journal (Refereed) Published
Abstract [en]

For evaluation of the role of interstrand hydrogen bonding for -hairpin stability, two cyclic peptides differing only in side chain hydroxy-to-methyl substitution were designed and synthesized on solid phase following the Fmoc-t-Bu-Trt protection strategy. Subsequent to cyclization in solution, combined computational and experimental ensemble analysis revealed higher conformational stability of the peptide capable of interstrand hydrogen bonding. Insight into β-Hairpin Stability: Interstrand Hydrogen Bonding | Request PDF. Available from: https://www.researchgate.net/publication/275142981_Insight_into_b-Hairpin_Stability_Interstrand_Hydrogen_Bonding [accessed Jul 11 2018].

Place, publisher, year, edition, pages
2013. Vol. 24, p. 2407-2410
National Category
Organic Chemistry
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URN: urn:nbn:se:uu:diva-356023OAI: oai:DiVA.org:uu-356023DiVA, id: diva2:1232445
Available from: 2018-07-11 Created: 2018-07-11 Last updated: 2018-07-11

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