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Relative frequencies of symptoms and risk factors among patients with chronic rhinosinusitis with nasal polyps using a case-control study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Otolaryngology and Head and Neck Surgery.ORCID iD: 0000-0001-6875-603X
Skaraborg Hosp, Dept Otorhinolaryngol, Skovde, Sweden.
Univ Gothenburg, Sahlgrenska Acad, Dept Otorhinolaryngol, Gothenburg, Sweden.
Skaraborg Hosp, Dept Otorhinolaryngol, Skovde, Sweden.
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2018 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, E-ISSN 1651-2251, Vol. 138, no 1, p. 46-49Article in journal (Refereed) Published
Abstract [en]

Objectives: The aim of this study was to investigate the relative frequency of important symptoms of chronic rhinosinusitis with nasal polyps (CRSwNP), the link between CRSwNP and the lower airways and the importance of smoking in CRSwNP.

Method: Three hundred and sixty-eight patients with CRSwNP and 1349 controls were recruited to the study and underwent a structured interview about symptoms from the upper and lower airways, and about smoking habits. Furthermore, all participants were clinically examined using nasal endoscopy.

Results: Due to interactions between the outcome variables, a multiple logistic regression model was fitted to the data. Nasal secretions, nasal blockage and impaired sense of smell were symptoms associated with CRSwNP. Furthermore, male gender, increasing age and asthma were also associated with the disease. Current smoking was less frequent among patients with CRSwNP.

Conclusion: By comparing symptoms and risk factors of patients with CRSwNP with those of a large population-based control group and testing them in a multiple logistic regression model, we have been able to generate data that address key research interests in CRSwNP.

Place, publisher, year, edition, pages
TAYLOR & FRANCIS LTD , 2018. Vol. 138, no 1, p. 46-49
Keywords [en]
Nasal polyps, asthma, smoking, chronic rhinosinusitis, signs and symptoms, respiratory
National Category
Otorhinolaryngology
Identifiers
URN: urn:nbn:se:uu:diva-354532DOI: 10.1080/00016489.2017.1366052ISI: 000428378700010PubMedID: 28826302OAI: oai:DiVA.org:uu-354532DiVA, id: diva2:1233117
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Region Västra GötalandAvailable from: 2018-07-16 Created: 2018-07-16 Last updated: 2018-07-16Bibliographically approved

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