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Oral treatment with yolk antibodies for the prevention of C. albicans infections in chemotherapy treated children: A feasibility study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. (biologisk struktur och funktion)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences. (biologisk struktur och funktion)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
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2005 (English)In: Food and Agricultural Immunology, ISSN 0954-0105, Vol. 16, no 1, 41-45 p.Article in journal (Refereed) Published
Abstract [en]

Cancer patients treated with chemotherapy often become neutropenic, which predisposes for oral and systemic C. albicans infections. The purpose of this feasibility study was to find out if gargling with anti- C. albicans immunoglobulin Y from egg yolk can prevent oral candidiasis in children, treated for acute lymphatic leukemia. Four patients gargled with the antibodies once a day during the induction phase of chemotherapy. None of four patients treated with IgY got any C. albicans infection. In the non- treated control and in a historic group, seven of thirteen patients had suspected C. albicans infection. This study indicates that anti- C. albicans IgY may prevent oral candidiasis in immunocompromized children.

Place, publisher, year, edition, pages
2005. Vol. 16, no 1, 41-45 p.
Keyword [en]
oral immunotherapy, yolk antibodies, C. albicans, children, acute lymphatic leukemia
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-86638DOI: 10.1080/09540100400003543OAI: oai:DiVA.org:uu-86638DiVA: diva2:126720
Available from: 2008-11-20 Created: 2008-11-20 Last updated: 2009-04-15Bibliographically approved

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