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Busseihydroquinones A-D from the roots of Pentas bussei
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2012 (English)In: Journal of Natural Products, ISSN 0163-3864, E-ISSN 1520-6025, Vol. 75, no 7, p. 1299-1304Article in journal (Refereed) Published
Abstract [en]

Four new naphthohydroquinones, named busseihydroquinones A-D (1-4), along with a known homoprenylated dihydronaphthoquinone (5), were isolated from the CH(2)Cl(2)/MeOH (1:1) extract of the roots of Pentas bussei. Although the genus Pentas is frequently used by traditional healers for the treatment of malaria, only marginal activities against the chloroquine-sensitive (D6) and the chloroquine-resistant (W2) strains of Plasmodium falciparum were observed for the crude root extract and the isolated constituents of this plant.

Place, publisher, year, edition, pages
2012. Vol. 75, no 7, p. 1299-1304
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Organic Chemistry
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URN: urn:nbn:se:uu:diva-368841DOI: 10.1021/np3002223PubMedID: 22709138OAI: oai:DiVA.org:uu-368841DiVA, id: diva2:1275517
Available from: 2019-01-06 Created: 2019-01-06 Last updated: 2019-08-08Bibliographically approved

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Erdélyi, Máté

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